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研究業績

稲田 利文 教授
松尾 芳隆 准教授
鈴木 亨 助教

松尾 芳隆 准教授 業績

原著論文

Narita, M.#, Denk, T.#, Matsuo, Y., Sugiyama, T., Kikuguchi, C., Ito, S., Sato, N., Suzuki, T., Hashimoto, S., Machová, I., Tesina, P., Beckmann, R., Inada, T.* (#Equal contribution)
A distinct mammalian disome collision interface harbors K63-linked polyubiquitination of uS10 to trigger hRQT-mediated subunit dissociation
Nat Commun.  
doi:10.1038/s41467-022-34097-9 (2022)

Li, S., Ikeuchi, K., Kato, M., Buschauer, R., Sugiyama, T., Adachi, S., Kusano, H., Natsume, T., Berninghausen, O., Matsuo, Y., Becker, T., Beckmann, R., Inada, T.
Sensing of individual stalled 80S ribosomes by Fap1 for nonfunctional rRNA turnover
Mol Cell  
doi:10.1016/j.molcel.2022.08.018 (2022) (Press release)

Alam, M., Shima, H., Matsuo, Y., Nguyen, CL., Matsumoto, M., Ishii, Y., Sato, N., Sugiyama, T., Nobuta, R., Hashimoto, S., Liu, L., Kaneko, MK., Kato, Y., Inada, T.*, Igarashi, K.*
mTORC1-independent translation control in mammalian cells by methionie adenosyltransferase 2A and S-adenosylmethionine
J Biol. Chem.  
doi: 10.1016/j.jbc.2022.102084 (2022)

Mita, Y., Uchida, R., Yasuhara, S., Kishi, K., Hoshi. T., Matsuo. Y., Yokooji. T., Shirakawa. Y., Toyama, T., Urano, Y., Inada, T., Noguchi, N., Saito, Y.
Identification of a novel endogenous long non-coding RNA that inhibits selenoprotein P translation
Nucleic Acids Res.  
doi: 10.1093/nar/gkab498 (2021)

Takehara, Y., Yashiroda H., Matsuo Y., Zhao X., Kamigaki A., Matsuzaki T., Kosako H., Inada T., Murata S.* 
The ubiquitination-deubiquitination cycle on the ribosomal protein eS7A is crucial for efficient translation
iScience  
doi: 10.1016/j.isci.2021.102145 (2021)

Matsuo, Y.* and Inada, T.*
Ribosome collision sensor Hel2 functions as preventive quality control in the secretory pathway
Cell Rep.
doi: 10.1016/j.celrep.2021.108877 (2021)

Buschauer, R.#, Matsuo, Y.#, Sugiyama, T., Chen, Y., Alhusaini, N., Sweet, T., Ikeuchi, K., Cheng, J., Matsuki, Y., Nobuta, R., Gilmozzi, A., Berninghausen, O., Tesina, P., Becker, T., Coller, J.*, Inada, T.*, Beckmann, R.* (#Equal contribution)
The Ccr4-Not complex monitors the translating ribosome for codon optimality
Science  
doi: 10.1126/science.aay6912 (2020) (Press release)

Matsuo, Y.#, Tesina, P.#, Nakajima, S., Mizuno, M., Endo, A., Buschauer, R., Cheng, J., Shounai, O., Ikeuchi, K., Saeki, Y., Becker, T., *Beckmann, R. and *Inada, T. (#Equal contribution)
RQT complex dissociates ribosomes collided on endogenous RQC substrate SDD1
Nat. Struc. Mol. Biol.  
doi: 10.1038/s41594-020-0393-9 (2020)

Sugiyama, T.1, Li, S.1, Kato, M.1, Ikeuchi, K., Ichimura, A., Matsuo, Y. and Inada, T.* (1Equal contribution)
Sequential ubiquitination of ribosomal protein uS3 triggers the degradation of non-functional 18S rRNA
Cell Rep.  
doi: 10.1016/j.celrep.2019.02.067. (2019)

Ikeuchi, K., Tesina, P., Matsuo, Y., Sugiyama, T., Cheng, J., Saeki, Y., Tanaka, K., Becker, T., Beckmann, R., Inada, T.
Collided ribosomes form a unique structural interface to induce Hel2‐driven quality control pathways
EMBO J.  
doi: 10.15252/embj.2018100276 (2019)

Matsuo, Y., Ikeuchi, K., Saeki, Y., Iwasaki, S., Schmidt, C., Udagawa, T., Sato, F., Tsuchiya, H., Becker, T., Tanaka, K., Ingolia, NT., Beckmann, R. and *Inada, T.
Ubiquitination of Stalled Ribosome Triggers Ribosome-associated Quality Control
Nat. Commun. 
doi: 10.1038/s41467-017-00188-1 (2017)

Matsuo, Y., Granneman, S., Thoms, M., Manikas, RG., Tollervey, D. and *Hurt, E.
Coupled GTPase and remodelling ATPase activities form a checkpoint for ribosome export
Nature.  
doi: 10.1038/nature12731 (2013)

Matsuo, Y., Morimoto, T., Kuwano, M., Loh, P., Oshima  T., Ogasawara, N.
The GTP-binding protein YlqF participates in the late step of 50S ribosomal subunit assembly in Bacillus subtilis
J Biol Chem.  
doi: 10.1074/jbc.M512556200 (2006)

Matsuo, Y., Oshima, T., Loh, P., Morimoto T., Ogasawara N.
Isolation and characterization of a dominant negative mutant of Bacillus subtilis GTP-binding protein, YlqF, essential for biogenesis and maintenance of the 50S ribosomal subunit

J Biol Chem.  
doi: 10.1074/jbc.M703894200(2007)

Loh, P., Morimoto, T., Matsuo, Y.,Oshima T., Ogasawara, N.  
The GTP-binding protein YqeH participates in biogenesis of the 30S ribosome subunit in Bacillus subtilis.

Genes Genet Syst.  
doi: 10.1266/ggs.82.281 (2007)

東京大学医科学研究所基礎医科学部門

RNA制御学分野

〒108-8639 東京都港区白金台4丁目6−1

Division of RNA and Gene Regulation

The Institute of Medical Science, The University of Tokyo

4-6-1, Shirokanedai, Minato-ku, Tokyo 108-8639, Japan

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